Beschrijving

Contributors to this volume focus on the fact that while reliable and sensitive detection of characteristic molecular markers for human exposure to chemical carcinogens is no longer a barrier to further study, the evaluation of the risk of developing a tumor following such exposures remains a difficult problem. Methods by which human exposure to carcinogens has been detected are described, including immunoassay techniques, physico-chemical methods and post-labelling assays. A number of studies are then discussed in which molecular markers are being used to assess exposure to environmental, occupational and iatrogenic carcinogens, and to relate this information to the type or incidence of cancers that occur.